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2021 Volume 12 Issue 4

Clinical and Pathoanatomical Aspects of Combined Chlamydial-Mycoplasma-Klebsiella Infection of Lambs


Anastasiya Sergeevna Metleva, Oksana Vladimirovna Smolovskaya, Anna Vyacheslavovna Semechkova, Anastasia Leonidovna Evstratenko
Abstract

An autopsy of lambs that died during the first two days after birth was carried out. Typical clinical disease signs were refusal to milk, lethargy, rounded formations in the middle third part of the neck measuring 11×7×8 (cm), and death. An autopsy revealed an acute expansion and paralysis of the heart, as a result of which congested phenomena in the organs in the pulmonary circulation (pulmonary and cerebral edema) were established; hemorrhagic inflammation of the kidneys, lymphoidulitis of deep cervical and mesenteric lymph nodes, acute hemorrhagic enterocolitis. The death of the lambs was caused by heart paralysis. In the process of the autopsy, samples of pathological material (lymph nodes, heart, lungs, liver, kidneys, spleen, and brain) were taken aseptically. The samples were subjected to PCR-diagnostics and microbiological studies at the Research Laboratory of Biochemical, Molecular Genetic Research, and Breeding of Farm Animals of the Kuzbass State Agricultural Academy; they were studied for the presence of infectious agents that can be transmitted transplacentally. As a result of studies of the internal organs of lambs, the presence of the following microorganisms was established: K. pneumoniae, Chlamydiacеae spp., Mycoplasma spp. The ability of K.pneumoniae to grow under anaerobic conditions, with the production of hemolysin, was studied as well, which indicates the ability to penetrate and develop in eukaryotic cells, incl. in intrauterine conditions.


How to cite this article
Vancouver
Metleva A S, Smolovskaya O V, Semechkova A V, Evstratenko A L. Clinical and Pathoanatomical Aspects of Combined Chlamydial-Mycoplasma-Klebsiella Infection of Lambs. J Biochem Technol. 2021;12(4):12-8. https://doi.org/10.51847/z7pZcYOFJi
APA
Metleva, A. S., Smolovskaya, O. V., Semechkova, A. V., & Evstratenko, A. L. (2021). Clinical and Pathoanatomical Aspects of Combined Chlamydial-Mycoplasma-Klebsiella Infection of Lambs. Journal Of Biochemical Technology, 12(4),12-18. https://doi.org/10.51847/z7pZcYOFJi
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative