2018 Volume 9 Issue 2 Special Issue
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Assessment of Pharmacoeconomics and Drug Usage Among Haemodialysis Patients, Baptist Hospital, Bangalore


Abstract

Objective: To analyses the prescribing pattern in haemodialysis patients and Pharmacoeconomics to assess QOL in haemodialysis patients.Methodology: This was a cross-sectional study conducted in patients undergoing haemodialysis at Dialysis center of tertiary care teaching hospital at Bangalore Baptist hospital (BBH) Hebbal, over a period of six months. Data was analyzed using statistical methods such as Kolmogorov Smirnov (KS) test, unpaired t-test and Analysis of Variance, Pearson correlation coefficient, SPSS version 18 and 20.Result:Total number of patients diagnosed as CKD undergoing dialysis during the study period was 50, of which 34(68%) were males and 16 (32%) were females with their mean age of 53.89 ±13.34 years and 39.05 ± 8.45 years respectively. Analysis of WHO core drug prescribing indicators showed that the average number of drugs prescribed per patient was 5. CKD was most commonly seen in males with significant statistical difference (P-value<0.001). Most common co-morbid condition associated with CKD was hypertension (16%) followed by diabetes mellitus (20%) and IHD (20%). Anticoagulant agent (100%) was the most commonly used drug, followed by antihypertensive drugs (94%), ulcer protective, calcium salt, multivitamins, erythropoietin, insulin, antiplatelet, oral hypoglycemic and statins. Patients on haemodialysis had a poorer QOL in all domains except for domain 4(environment).Conclusion: Current study provides valuable insight about the overall pattern of drug use profile in haemodialysis population. heparin and amlodipine has the highest cost among all commonly used drugs. In haemodialysis patient the lowest QOL score was observed with social domain (8.2) followed by physical (13.2) and psychological (13.9) domain. Highest score was seen with environmental (21.5) domain.


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