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2021 Volume 12 Issue 2

Aphanizomenon flos-aquae Protects against the Biochemical Changes Induced in Rats Consuming a Mixture of Food Additives


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Abstract

Various additives are added to food products to attain the desired properties such as flavor, preservation, and sweetening. The goal of this research was to investigate the biochemical alterations in the rats consuming a food additives mixture (FAM) containing sodium nitrate, fast green, and glycine; and the potential protective impact of Aphanizomenon flos-aquae (A. flos-aquae). Thirty male albino rats were classified into three equal groups (n=10) Group I: the control, group II: FAM; group III: FAM + A. flos-aquae. After 30 days, the biochemical analysis revealed a significant increase in the liver (ALT and AST) and kidney (creatinine and urea) toxicity markers. The FAM significantly increased total cholesterol, triglycerides, and low-density lipoprotein. The mixture significantly decreased body weight, high-density lipoprotein, total protein, albumin, globulin, and testosterone. The FAM had no impact on serum glucose, insulin, and thyroid hormones (T3 and T4). A. flos-aquae significantly protected against these biochemical alterations. The current findings showed that A. flos-aquae can protect against the severe impacts of a FAM on key biochemical markers.


How to cite this article
Vancouver
Helal EGEE, Saaty AH, Mohamed AAH, Abdelaziz MA. Aphanizomenon flos-aquae Protects against the Biochemical Changes Induced in Rats Consuming a Mixture of Food Additives. J Biochem Technol. 2021;12(2):83-91. https://doi.org/10.51847/tOl0ZkPv5Y
APA
Helal, E. G. E. E., Saaty, A. H., Mohamed, A. A. H., & Abdelaziz, M. A. (2021). Aphanizomenon flos-aquae Protects against the Biochemical Changes Induced in Rats Consuming a Mixture of Food Additives. Journal of Biochemical Technology, 12(2), 83-91. https://doi.org/10.51847/tOl0ZkPv5Y
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

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FOCUS AND SCOPE
Journal Of Biochemical Technology Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative