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2021 Volume 12 Issue 3

Antioxidant Activity of a Multicomponent Remedy Based on Extracts of Purifying Pelargonium Root, Oregano, and IVY


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Abstract

Naturally-occurring antioxidants are of particular interest because of their ability to trap free radicals and prevent destructive processes caused by oxidative stress. The purpose of this study was to investigate the antioxidant activity of three herbal extracts from the root of pelargonium purifying (Pelargonіum sіdoіdes), ivy leaves (Hedera helix L., Hedera caucasigena Pojark) and oregano (Origanum vulgare L.) with different combinations of their ratios. These plants were chosen based on their wide use by traditional medicine healers to treat various diseases. Extraction conditions were selected for each plant separately, and ethanol was used as an extractant. Thick extracts of the studied plants were dried to obtain dry extracts with a moisture content not exceeding 1%. A definition of antioxidant activity (AA) of the studied multicomponent drug solutions was performed in vitro using DFPH (2,2-diphenyl-1-picrylhydrazyl) free-radical method. The results obtained show high AA of solution #7 in which the ratio of active pharmaceutical ingredients was almost the same (tannins: hederocoside: thymol and carvacrol = 1: 1: 1.25). Solutions #3 and #4, which contained 1.4 mg of tannins, 1 mg of hederocosids, and 3 mg of thymol and carvacrol in 100 ml of ethanol, also showed high AA. Multicomponent drugs #5 and 6 were the least effective. Thus, the antioxidant activity of multicomponent drugs based on extracts from purifying pelargonium root, common ivy leaf, and common oregano herb was investigated. The results of the research indicate the promising use of multicomponent drugs #7, 3, and 4 as antioxidant remedies.


How to cite this article
Vancouver
Bryda O, Stadnytska N. Antioxidant Activity of a Multicomponent Remedy Based on Extracts of Purifying Pelargonium Root, Oregano, and IVY. J Biochem Technol. 2021;12(3):53-8. https://doi.org/10.51847/Jxo7cRM3sl
APA
Bryda, O., & Stadnytska, N. (2021). Antioxidant Activity of a Multicomponent Remedy Based on Extracts of Purifying Pelargonium Root, Oregano, and IVY. Journal of Biochemical Technology, 12(3), 53-58. https://doi.org/10.51847/Jxo7cRM3sl
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative