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2011 Volume 3 Issue 2

Adsorption of hemoglobin, fatty acid and glucose to iron nanoparticles as a mean for drug delivery


Abstract
Recent research in biomedicine has documented the application of iron-based nano-particles in supplying the human body with essential nutrients or in drug delivery systems.   In this work, the possibility of using iron nanoparticles sorption of biomaterial, such as hemoglobin, cholesterol, triglyceride, serum albumin, and glucose, to cure some specific syndromes have been studies. Bradford assay was used for protein adsorption measurement in supernatant, and FTIR was used for studying the ligands attached to iron nanoparticle. Cholesterol kit and Triglyceride kit were used to measure the cholesterol and triglyceride in supernatant. The result showed that glucose was adsorbed, and the remaining polysaccharide left in supernatant was 42%. Also sorption of triglyceride, cholesterol and serum albumin by nanoparticles was 69%, 73.3% and 87% respectively. FTIR showed hemoglobin being adsorbed to nanoparticles as a ligand. These results indicate that iron nano particles have the capability of being used as a delivery system for biomaterials.  

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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

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Welcome to the Journal of Biochemical Technology, a prestigious international double-blind peer-reviewed journal dedicated to advancing excellence in biochemical, biotechnological, and bioinformatics research with direct applications in biology and medicine.

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The Journal of Biochemical Technology is dedicated to publishing innovative research in the fields of biochemistry, biotechnology, and bioinformatics with direct applications in biology and medicine.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative