Quick access

Full HTML PDF
Share Article:
2021 Volume 12 Issue 3

Abnormal Hematological Characteristics among Sudanese Children with Down Syndrome


, , , ,
Abstract

Hematological reference values are very important for diagnosing and interpreting the results and decision-making to assess the hematological parameters among children diagnosed with Down Syndrome in Khartoum State-Sudan. A total of 60 subjects were enrolled in the study. Of them, 30 individuals were patients with Down Syndrome, and 30 apparently healthy individuals were considered control throughout the period from (September 2020 to December 2020). A total of 2.5 ml of venous blood were collected in EDTA containers and investigated using SysmexKX-21N analyzer; the data were analyzed using SPSS – Independent T-test at a 5% level of significance. study revealed that the mean of MCHC and Platelets count for Down Syndrome patients were significantly (P value≤0.00) decreased (32.10±2.42, and 183.27±99.10). Moreover, no significant change in RBCs count, HB, MCV, HCT, MCH, and WBCs values for both groups. The study concluded that Down Syndrome has an obvious effect on some hematological profiles by decreasing Platelets and MCHC. Still, there is no effect on RBCs TWBCs and other RBCs indices.


How to cite this article
Vancouver
Ali RIK, Abdallah EI, ELmobark M, Omer AE, Eltayeb LB. Abnormal Hematological Characteristics among Sudanese Children with Down Syndrome. J Biochem Technol. 2021;12(3):74-7. https://doi.org/10.51847/2OB9WmvN5N
APA
Ali, R. I. K., Abdallah, E. I., ELmobark, M., Omer, A. E., & Eltayeb, L. B. (2021). Abnormal Hematological Characteristics among Sudanese Children with Down Syndrome. Journal of Biochemical Technology, 12(3), 74-77. https://doi.org/10.51847/2OB9WmvN5N
INDEXING
SCIRUS, Chemical Abstracts, EBSCOhost databases, Genamics JournalSeek, ABCD Journl Index and many other international scientific databases.

JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

Publish with us


Deniz Publication
Guzelyali Mah. Sahilyolu Cad.Defne Sok. No: 7, 34903 Pendik, Istanbul
Email: [email protected]
Tell: +905344990778

Publishing steps

1.Prepare
your paper
2.Submit
and revise
3.Track
your research
4.Share
and promote
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative