Quick access

Full HTML PDF
Share Article:
2021 Volume 12 Issue 3

Abnormal Hematological Characteristics among Sudanese Children with Down Syndrome


Romisa Ibrahiem Karkab Ali, Elharam Ibrahim Abdallah, Mohmmed ELmobark, Alaa Eltayeb Omer, Lienda Bashier Eltayeb
Abstract

Hematological reference values are very important for diagnosing and interpreting the results and decision-making to assess the hematological parameters among children diagnosed with Down Syndrome in Khartoum State-Sudan. A total of 60 subjects were enrolled in the study. Of them, 30 individuals were patients with Down Syndrome, and 30 apparently healthy individuals were considered control throughout the period from (September 2020 to December 2020). A total of 2.5 ml of venous blood were collected in EDTA containers and investigated using SysmexKX-21N analyzer; the data were analyzed using SPSS – Independent T-test at a 5% level of significance. study revealed that the mean of MCHC and Platelets count for Down Syndrome patients were significantly (P value≤0.00) decreased (32.10±2.42, and 183.27±99.10). Moreover, no significant change in RBCs count, HB, MCV, HCT, MCH, and WBCs values for both groups. The study concluded that Down Syndrome has an obvious effect on some hematological profiles by decreasing Platelets and MCHC. Still, there is no effect on RBCs TWBCs and other RBCs indices.


How to cite this article
Vancouver
Ali R I K, Abdallah E I, ELmobark M, Omer A E, Eltayeb L B. Abnormal Hematological Characteristics among Sudanese Children with Down Syndrome. J Biochem Technol. 2021;12(3):74-7. https://doi.org/10.51847/2OB9WmvN5N
APA
Ali, R. I. K., Abdallah, E. I., ELmobark, M., Omer, A. E., & Eltayeb, L. B. (2021). Abnormal Hematological Characteristics among Sudanese Children with Down Syndrome. Journal Of Biochemical Technology, 12(3),74-77. https://doi.org/10.51847/2OB9WmvN5N
INDEXING
ESCI, SCIRUS, BiologyBrowser, Chemical Abstracts, CABI, Intute catalogue, Science Central, EBSCOhost databases, Google Scholars, Genamics JournalSeek, Open J gate, Ulrich's, ResearchGate, Academic Journals Database, CASSI, ACS (American Chemical Society), CiteFactor, and many other international scientific databases.

JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

Publish with us

Call for papers

Issue 4 Volume 12 - 2021

Publishing steps

1.Prepare
your paper
2.Submit
and revise
3.Track
your research
4.Share
and promote
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative