Introduction: Dialysis inadequacy is one of the determinants of morbidity and mortality of hemodialysis patients. Raising dialysis adequacy improves the prognosis of hemodialysis patients. Since the hemodialysis efficiency depends on the dialysis adequacy, it is essential to investigate the factors affecting the hemodialysis adequacy and evaluate the extent of hemodialysis adequacy. Therefore, this article aimed to study the extent of hemodialysis adequacy of the patients visiting the hemodialysis center of Ostad Motahari Hospital of Jahrom, Iran. Method: This is descriptive, cross-sectional study. The study sample consisted of hemodialysis patients visiting Ostad Motahari Hospital of Jahrom, Iran. A total of 95 non-emergency hemodialysis patients entered the study in 2016. Demographic characteristics, age, gender, weight, pre-hemodialysis and post-hemodialysis blood urea nitrogen (BUN), and length of hemodialysis were taken into account. Hemodialysis adequacy was investigated based on kv/t and URR levels. The data were analyzed using SPSS21, descriptive statistics (mean and standard deviation), and inferential statistics (chi-square, Mann-Whitney, and Wilcoxon). Results: 54.7% of the patients were male and 45.3% were female. Chi-square test results showed that hemodialysis adequacy of men and women was different (P<0.001). 83.3% and 78.9% of patients had hemodialysis adequacy in terms of Kv/t and URR levels, respectively. Length of hemodialysis in each session had no significant relationship with hemodialysis adequacy; however, age and weight had a significant relationship (P<0.001). Conclusion: The results showed that 83.3% and 78.9% of patients had hemodialysis adequacy at Kv/t and URR levels, respectively. Therefore, hemodialysis adequacy was optimal in Jahrom, Iran.