The present study was undertaken to evaluate the leaf extracts of Carica papaya (Linn.) on hematologic and biochemical changes occurring due to irradiation of mice to sub-lethal doses of Electron Beam Radiation (EBR).The immunomodulatory response of C. papaya (Linn.) extract to the radiological effects by determining the levels of interleukin-6. The serum total antioxidants, lipid peroxidation and the biochemical changes in liver and kidney function were assessed. Reduction in the hematological
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In an attempt to improve the level of purity of buffalo lung cathepsin B, we have modified the earlier procedure by incorporating CM- Sephadex C-50 ion exchange chromatography and rechromatography on Sephacryl S-200 column. Appearance of a single band on SDS-PAGE under reducing and non-reducing conditions showed that the enzyme exists in a single chain molecule. Molecular weight of purified cathepsin B was determined to be 23800 and 25400 by SDS-PAGE and gel filtration, respectively. The enzyme,
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