Artificial neural networks (ANN) and response surface methodology (RSM) were used to build a model to describe the effects of four independent variables (moisture content, concentrations of glucose, ammonium nitrate and methionine) on the yield of cephalosporin C
(CPC) from Acremonium chrysogenum under solid state fermentation. The respective uses of RSM and ANN were found to be effective in locating the optimum conditions within the range
fixed from the preliminary runs. When compared with the
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Efforts towards application of Supercritical Carbon Dioxide (SCCO2) extraction in Malaysia are still at its infancy stage. More research has actively on-going to explore its potential performance on a bigger scale (industrial scale) so that it will provide a better alternative method of extraction compare to the present practice using organic solvent extraction. SC-CO2 has been proven on laboratory and pilot-scale as an effective extraction technique for large types of bio-materials such as herb
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Bioimmobilization with sol-gel method is a complicate system, involving many parameters that can affect sol-gel structure and immobilized biomolecules activity. In this study, trypsin, a model enzyme, was entrapped into sol-gel glasses produced from tetraethoxysilane (TEOS) and water to study the relationships between the immobilization parameters, namely ratio of water to TEOS, volume of poly (ethylene glycol) (PEG), concentration of buffer solution, pH of buffer solution by using statistical m
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CMPP Database (Central Metabolic Pathway Promoter Database) consists of manually annotated regulatory sequences/motif of genes
controlling Metabolic Pathways (http://cmpp.biodbs.info) such as Glycolysis’ and Krebs’ cycle. The CMPP software package written in Microsoft Visual Basics & MS Access was also developed for searching & updating the CMPP database. This database was
further used to study the relationship between 10 transcription factors involved in the non-coding upstream region of CM
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Database of Biological/Bioinformatics Databases (DBD) is a collection of 1669 databases and online resources collected from
NAR Database Summary Papers (http://www.oxfordjournals.org/nar/database/a/) & Internet search engines. The database has been developed based on 437 keywords (Glossary) available in
http://falcon.roswellpark.org/labweb/glossary.html. Keywords with their relevant databases are arranged in alphabetic order which enables quick accession of databases by researchers. Database des
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