Preparation of Molecularly Imprinted Polymers Coupled with Magnetic Nanoparticles for the Selective Extraction of Propranolol from Aqueous Solution of Propranolol, Atenolol and Metoprolol

Mehdi Samizadeh , Mahmoud Ebrahimi and Mehdi Pordel


In this work, highly selective molecularly imprinted polymers (MIPs) of propranolol on the internal surface of hollow fiber were prepared. The resulting MIP coated MNP were used as dispersive solid phase micro extraction (SPME) fiber coupled with HPLC-UV for the selective extraction and detection of propranolol. Encouraging result was obtained. Method was evaluated and enrichment factors, relative standard deviations and linearity ranged for propranolol 918.8, 2.9% and 25-3000 were obtained, respectively.


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