Background: Dyslipidemia is the first modifiable risk factor for cardiovascular disease. Chlorogenic acid which is abundantly found in Green Coffee Bean has a significant anti-oxidant and anti-inflammatory properties. Objectives: The aim of this study was investigating the effects of Green Coffee Bean Extract (GCBE) on some biomarkers of dyslipidemic patients. Methods: This study is a randomized, placebo-controlled, clinical trial. 70 subjects were assigned to use 800 mg/day GCBE supplements or placebo for 8 weeks, to examine Anthropometric indices, Lipid Profile and High-sensitivity C-reactive Protein. Results: GCBE supplementation significantly decreased weight, visceral fat and hs-CRP and significantly increased HDL-C level in intervention group (p<0.05). Conclusion: GCBE supplement may improve weight, visceral fat, hs-CRP and HDL-C but there were no positive effects on triglyceride, total cholesterol and LDL-C.
