Rivers are the main sources of water supply for various uses, so investigating the hydraulic and sediment conditions of rivers is of great importance. Understanding the morphology changes in rivers is necessary due to the complex process of erosion and sedimentation of rivers as well as the importance of river’s morphology changes in organization of flood control and design of hydraulic structures. The Karun River is in Khuzestan province and has a meander pattern; also due to the formation of islands and sedimentation of the river within the city of Ahvaz, an increase in water level is observed during the floods. In this study, using the two-dimensional software of CCHE2D and assuming the existence of shortcuts, we have attempted to remove the meanders of Choneibeh and Krishan 2. The hydraulic and sedimentary results show that the removal of meanders causes an increase in energy slope of the river, flow rate, and thereby an increase in erosion. According to the predictions of the model, the average flow rate is increased by 50% compared to the current path, which reduces the sedimentation for 40%.