The target of this research is the investigation of the relation between Metacognitive beliefs and cognitive styles with test anxiety among students suffering from cancer. The statistical population of the research included all the students who were studying in different universities of Tehran. 75 of them were selected by the method of convenience sampling and were assessed by using metacognitive beliefs, cognitive styles and test anxiety questionnaires. Then, the collected data were analyzed using multivariate regression. The findings of the study reveal that generally there is a significant relationship between metacognitive beliefs and cognitive styles with test anxiety of students suffering from cancer. In other words, the results indicate that metacognitive beliefs and cognitive styles specify almost 23.4% and 15.2% of “test anxiety” changes in students, respectively.