In aquaculture the oral route of vaccination is more feasible than immersion and injection routes. In oral vaccination, the vaccine is incorporated in feeds. In this case, palatability and water stability of the feed incorporated with vaccines and the influence of the feed incorporated with vaccines on growth performance of fish is important. In this study, for water stability test, 2 g of biofilm feed-based, free-cell feed-based and commercial pellets as control was put in 100 ml of water and were incubated at 30°C. Water stability of the feed was measured for various times from 1 to 7 hours. Also for evaluating the palatability of the different kinds of pellets, fishes in different groups were fed with 50 pellets of different kind of feeds in each aquarium. No any significant difference was observed in different hours of water stability of vaccine incorporated and commercial pallets. For determining the growth performance of the different type of the feed on red tilapia 50 ± 2 g fish were divided in different aquarium and fed with different kind of feeds for four weeks. Results showed no any significant difference between palatability of the vaccine incorporated and commercial pellets. In addition growth performance parameters showed no any significant differences between fish fed by commercial and feed incorporated with vaccines.
