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2020 Volume 11 Issue 1

Electro-Metabolic Aberrations in New Zealand Rabbit (Dose-Dependent Cuniculus) Induce by Chloropyrifos


Iniobong R. Inyang, D.U. Tegu, Sylvester C. Izah
Abstract

The aim of this study was to unveil the effect of Chloropyrifos on Oryclotagus cuniculus electrolytes and metabolites. Twenty-four of the probe organism (mean weight, 1.8 – 2.00kg) were acclimatized to laboratory conditions for 14 days and then exposed to varying concentrations of the toxicant (1.00mgl-1, 2.00 mgl-1 and 3.00 mgl-1) in a renewal bioassay technique for 14 days. Samples were collected and analyzed following standard protocol. Results of blood electrolytes (K+ and Na+) values were significant (p< 0.05), overt fluctuation and diminution of values were recorded. A clear stabilization of values characterized Na+ in the muscle, while Ca2+ values showed a significant deviation from the control. Cortisol in the brain and liver concentration were significant compared to the control group akin to brain and liver triglycerides. Essentially, triglyceride values decreased down in the experimental group (in a dose-dependent pattern). This report unveiled the hazards of pesticide use and the imperative of minimizing pesticide use or discovering pesticides that are safe with minimal impact on organisms.


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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative