Introduction: Hypertension is one of the main causes of mortality and need to managing by the patients. The main question is that, whether patients’ health literacy could play a role in management of hypertension; thus this study was conducted to assess correlation between health literacy and self-management in patients with hypertension. Materials and Methods: This is a descriptive-correlational study which was done on 200 patients with hypertension referring to Farshchian hospital of Hamadan during January 2017 to May 2018 by convenience sampling method. The collected data include demographic, health literacy (questionnaire of Iranian health literacy) and hypertension management questionnaire. Mean arterial blood pressure was determined by researcher. The data was analyzed by spss/24 software, T- test, chi-square correlation coefficient and regression analysis tests. Findings: The mean arterial blood pressure in these patient was 98.6 12 mmHg. The status of health literacy was on average level in 89.5 percent of patients. The health literacy had a direct and significant relationship with behaviors of self – regulation (r=0.482, P<0.0001), self- monitoring (P<0.0001, r=0.387) reaction to disease (P<0.001, r=0.368), adherence to pharmaceutical regime (r= 0.153, P=0.03) and self - care (r=0.210, P=0.003). Conclusion: Health literacy had a direct relationship with hypertension. the patients with higher health literacy could better control their disease.
