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2010 Volume 2 Issue 5 Special Issue

Box counting method in recording, processing and evaluation of genomic signals


Abstract
Fractals are geometrical shapes with noninteger dimension andinvariance against change of scale factor. For each geometricalshape, a single parameter - dimension - can be calculated. Forcalculation, Box Counting Method (BCM) was chosen.Determination of dimension on one level of resolution is notsufficient, it is necessary to subsequently process it and determine multifractal coefficient. Aim of our interest consists in analysis of images obtained from a linear sequence of DNA code. For analysis itself, sequences of Homo sapiens and Citrobacter youngae were chosen. Results of calculation are fractal coefficients derived from dimensions of generated structures. This result enables to introduce criterion for sequences determination. Graphical outputs may bealso represented as multidimensional alternative transformation of linearly recorded genomic signal. Algorithms were developed in computational environment MATLAB. Data were downloaded from a public database EMBL (ESI) and GenBank (NCBI).

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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative