Background: Albumin is a low weight protein which regulating the volume and extracellular fluid balance with its role in plasma oncotic pressure. Protein malnutrition, severe inflammation, renal and hepatic failure could cause low serum level of albumin, on the other hand albumin intravenous administration savior in critically ill patients. According to its cost it is so important to use this valuable drug in correct indication. Method: this cross-sectional, prospective study was conducted for 1 year in Baghiatallah Alazam hospital. All patients received albumin in all hospital ward were included and data was gathered according to the designed form. Finally, all data in similar month of 2016 and 2017 year were compared and analyzed by version 16 of SPSS. Result: 264 patients with mean age of 57 y/o were enrolled in this study. All the prescription was matched to the mentioned indication in designed form. Plasmapheresis and nephrotic syndrome were the most frequent cause of albumin prescription, consequently kidney transplantation ward was utilized the highest number of albumin. total of used vials in 2017 fallen more than half in comparison with 2016. Conclusion: The aim of this study was to evaluate the pattern of albumin use in 17 sections of Shariati Hospital, which resulted in a significant percentage of uncontrolled and unreasonable administration of this drug in these patients was in line with other studies all over the world. Therefore, continuing studies of DUE, although it costs, are necessary because it benefits the health system in the long run. The role of hospital pharmacists in reducing drug misuse and conducting DUE studies is deniable.
