TY - JOUR T1 - Information Generation Rate and its Relationship with the Entropy of Non-Linear Models: Covid-19 Case, Peru 2020 A1 - Danny Villegas Rivas A1 - Manuel Milla Pino A1 - Salli Villegas Rivas A1 - Erick Delgado Bazan A1 - Yary Pérez Pérez A1 - Zadith Garrido Campaña A1 - Martín Grados Vasquez A1 - Cesar Osorio Carrera A1 - Luis Ramírez Calderón A1 - José Paredes Carranza A1 - Ricardo Shimabuku Ysa JF - Journal of Biochemical Technology JO - J Biochem Technol SN - 0974-2328 Y1 - 2020 VL - 11 IS - 4 SP - 8 EP - 14 N2 - In this paper, entropy was studied in non-linear models including exponential, Gompertz, and logistic, to estimate epidemiological parameters of interest in data from confirmed cases of infection by COVID-19 in Peru. The data related to the spread of COVID-19 in Peru comes from the information available on the INS-Peru institutional portal (2020). The Akaike information criterion (AIC) and the residual standard error (ERR) were considered to evaluate the entropy of the models. The estimation of the parameters of the models was carried out using maximum likelihood and by the Bootstrap method. The results showed that the entropy of the models is related to the information generation rate, associated with the differential in the number of tests applied. Entropy severely affected maximum likelihood estimators. The Bootstrap estimators showed better performance against EMV with the estimated peak of confirmed cases. Bootstrap estimators were significantly affected by sample size, especially when n ≤ 10. The results of this research suggest considering the entropy and the information generation rate (differential in the application of tests for the diagnosis of COVID-19 in Peru), as well as the use of Bootstrap estimators as an alternative to estimate parameters of epidemiological models. UR - https://jbiochemtech.com/article/information-generation-rate-and-its-relationship-with-the-entropy-of-non-linear-models-covid-19-case-peru-2020 ER -