TY  - JOUR
T1  - Diabetic Ketoacidosis Approach in the Emergency Department
A1  - Bayan A. Almusailhi
A1  - Najdi I. Najdi
A1  - Sahira J. Al-Nahari
A1  - Ali K. Aljifry
A1  - Saud A. Alyabis
A1  - Omar O. A. Aljohani
A1  - Angham G. Alharbi
A1  - Mohammad A. Turkistani
A1  - Mohammed M. A. Alshahrani
A1  - Arwa A. Alshammari
A1  - Faisal M. Murayr
JF  - Journal of Biochemical Technology
JO  - J Biochem Technol
SN  - 0974-2328
Y1  - 2020
VL  - 11
IS  - 1
SP  - 131
EP  - 134
N2  - Background: Diabetic ketoacidosis (DKA) is an endocrinological emergency that occurs as a direct result of a total or relative deficiency of insulin and is potentially life-threatening. Lack of insulin results in attenuation of the other regulatory hormones. Objectives: In this paper, we will review the available literature discussing the features, diagnosis, and emergency management of DKA. Methodology: We conducted the literature search within the PubMed database using the keywords: “Ketoacidosis” and “DKA treatment” and “insulin” and “diabetic” with dates from 1990 to 2020. Review: DKA presents clinically in a triad of metabolic acidosis, hyperglycemia, and hyperketonemia, and/or hyperketouria. In most cases, DKA is accompanied by a varying level of circulatory collapse. Individuals who suffer from type 1 diabetes mellitus (T1DM) that is poorly controlled are by far the most vulnerable to DKA. The management goals of DKA revolve around the control of four different imbalances which are (1) hyperglycemia, (2) hypovolemia, (3) electrolytes imbalance, and (4) management of precipitating factors. Conclusion: In conclusion, the management of DKA is complex and needs cautious attention while restoring glucose level, hydration status, and electrolytes imbalance. Emergency physicians are a cornerstone in the management of DKA and should be aware of its importance.
UR  - https://jbiochemtech.com/article/diabetic-ketoacidosis-approach-in-the-emergency-department
ER  -