TY  - JOUR
T1  - Metabolic Dysregulation in Women with Unexplained Infertility and Pregnancy Loss
A1  - Anastasia Evgenievna Verstova
A1  - Olga Sergeevna Reznikova
A1  - Iman Rizvanovna Dikaeva
A1  - Rayana Movsarovna Tsamaeva
A1  - Amal Youssef-Adis
A1  - Fatima-Zakhra Umar Salek
A1  - Rayana Akhmedovna Vashaeva
A1  - Khava Ruslanovna Radueva
A1  - Magomed-Ramzan Nurmagomedovich Baysagurov
A1  - Aishat Bislanovna Mustapayeva
JF  - Journal of Biochemical Technology
JO  - J Biochem Technol
SN  - 0974-2328
Y1  - 2025
VL  - 16
IS  - 4
DO  - 10.51847/u0ogbqb1Im
SP  - 27
EP  - 37
N2  - This prospective cohort study investigates the association between metabolic disturbances and reproductive dysfunction in women with idiopathic infertility and recurrent pregnancy loss (RPL). Conducted at the Perinatal Centre of Grozny from 2022 to 2025, the study involved 240 women allocated into three groups: Group 1 (n=120) with idiopathic infertility/RPL, Group 2 (n=60) with tubal factor infertility, and a control Group 3 (n=60) of fertile women. All participants underwent a comprehensive assessment, including anthropometric measurements, hormonal profiling, evaluation of insulin resistance (HOMA-IR, QUICKI), adipokine status (leptin, adiponectin), oxidative stress markers (MDA, SOD), and transvaginal ultrasonography. The results revealed a distinct metabolic phenotype in Group 1, characterized by significantly higher BMI, waist circumference, and markers of insulin resistance (HOMA-IR: 3.8 vs. 1.4 in controls, p
UR  - https://jbiochemtech.com/article/metabolic-dysregulation-in-women-with-unexplained-infertility-and-pregnancy-loss-hcnciag11h8w5es
ER  -