%0 Journal Article
%T Metabolic Dysregulation in Women with Unexplained Infertility and Pregnancy Loss
%A Anastasia Evgenievna Verstova
%A Olga Sergeevna Reznikova
%A Iman Rizvanovna Dikaeva
%A Rayana Movsarovna Tsamaeva
%A Amal Youssef-Adis
%A Fatima-Zakhra Umar Salek
%A Rayana Akhmedovna Vashaeva
%A Khava Ruslanovna Radueva
%A Magomed-Ramzan Nurmagomedovich Baysagurov
%A Aishat Bislanovna Mustapayeva
%J Journal of Biochemical Technology
%@ 0974-2328
%D 2025
%V 16
%N 4
%R 10.51847/u0ogbqb1Im
%P 27-37
%X This prospective cohort study investigates the association between metabolic disturbances and reproductive dysfunction in women with idiopathic infertility and recurrent pregnancy loss (RPL). Conducted at the Perinatal Centre of Grozny from 2022 to 2025, the study involved 240 women allocated into three groups: Group 1 (n=120) with idiopathic infertility/RPL, Group 2 (n=60) with tubal factor infertility, and a control Group 3 (n=60) of fertile women. All participants underwent a comprehensive assessment, including anthropometric measurements, hormonal profiling, evaluation of insulin resistance (HOMA-IR, QUICKI), adipokine status (leptin, adiponectin), oxidative stress markers (MDA, SOD), and transvaginal ultrasonography. The results revealed a distinct metabolic phenotype in Group 1, characterized by significantly higher BMI, waist circumference, and markers of insulin resistance (HOMA-IR: 3.8 vs. 1.4 in controls, p
%U https://jbiochemtech.com/article/metabolic-dysregulation-in-women-with-unexplained-infertility-and-pregnancy-loss-hcnciag11h8w5es