TY  - JOUR
T1  - Consortium of Biologically Active Substances in Biotechnological Products and Their Clinical Trial
A1  - Lobach Evgenia Yurievna
A1  - Tokhiriyon Boisjoni
A1  - Poznyakovsky Valery Mikhailovich
A1  - Cherentsova Galina Georgievna
A1  - Agababayev Mushfiq Saday Oglu
JF  - Journal of Biochemical Technology
JO  - J Biochem Technol
SN  - 0974-2328
Y1  - 2025
VL  - 16
IS  - 2
DO  - 10.51847/CNFeCcajRB
SP  - 141
EP  - 147
N2  - This article examines approaches to the comprehensive treatment and prevention of colpitis and vulvovaginal candidiasis (VVC), with a focus on the use of dietary supplements (DS). The crucial role of vaginal microflora imbalances in the development of colpitis is highlighted, justifying the use of probiotics and biocomplexes. Specific attention is given to various DS formulations, such as a Phytocomplex with black cumin oil, an Isoflavone Complex with Probiotics, a Biocomplex with fermented dietary fiber, an Intimate Mucous Membrane Care Spray, and a Biocomplex for metabolic detoxification and intestinal biocenosis correction. The composition of these DS, including plant components, probiotic strains, vitamins, microelements, and other biologically active substances, is detailed. The mechanisms of action of DS components, like the antioxidant, anti-inflammatory, and antimicrobial properties of flavonoids, are discussed, along with the role of probiotics in restoring vaginal and intestinal microflora.

Furthermore, the results of a clinical study evaluating the effectiveness of different treatment regimens using these DS in patients with chronic colpitis are presented. The study demonstrates that the proposed treatment programs, with various DS combinations, effectively alleviate symptoms and improve laboratory parameters, particularly by normalizing the microflora and eliminating pathogens. This suggests the potential of these programs for comprehensive treatment and prevention of colpitis, VVC, and other conditions associated with microbiota imbalances.
UR  - https://jbiochemtech.com/article/consortium-of-biologically-active-substances-in-biotechnological-products-and-their-clinical-trial-4tdsefirsfi0qyb
ER  -